Trelstar LA

Pronunciation: TRIP-toe-REL-in
Generic Name: Triptorelin
Brand Name: Examples include Trelstar Depot and Trelstar LA

Trelstar LA is used for:

Treating symptoms of advanced prostate cancer. It may be used for other conditions as determined by your doctor.

Trelstar LA is a synthetic analogue of gonadotropin-releasing hormone (GnRH) agonist. It works by decreasing the production of certain hormones, which reduces testosterone levels in the body.

Do NOT use Trelstar LA if:

• you are allergic to any ingredient in Trelstar LA, to GnRH, or to another GnRH agonist (eg, goserelin)


• you are pregnant, may become pregnant, or are breast-feeding

Contact your doctor or health care provider right away if any of these apply to you.

Before using Trelstar LA:

Some medical conditions may interact with Trelstar LA. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you have a history or urinary problems (eg, blockage of the bladder or ureters), spinal cord problems, abnormal growths on or near the spine or spinal cord, heart problems, blood vessel problems, a stroke, diabetes, or high blood sugar

Some MEDICINES MAY INTERACT with Trelstar LA. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Medicines that increase prolactin levels in the blood (eg, promethazine) because the effectiveness of Trelstar LA may be decreased

This may not be a complete list of all interactions that may occur. Ask your health care provider if Trelstar LA may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Trelstar LA:

Use Trelstar LA as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Trelstar LA is usually given as an injection at your doctor's office, hospital, or clinic. If you will be using Trelstar LA at home, a health care provider will teach you how to use it. Be sure you understand how to use Trelstar LA. Follow the procedures you are taught when you use a dose. Contact your health care provider if you have any questions.


• Trelstar LA is injected into the muscle.


• Rotate the injection site. Do not inject into an area of skin that is red, hard, or bruised, or has scars or stretch marks.


• Do not use Trelstar LA if it contains particles, is cloudy or discolored, or if the vial is cracked or damaged.


• Keep this product, as well as syringes and needles, out of the reach of children and pets. Do not reuse needles, syringes, or other materials. Ask your health care provider how to dispose of these materials after use. Ask your doctor, nurse, or pharmacist to explain local regulations for selecting an appropriate container and properly disposing of the container when full.


• If you miss a dose of Trelstar LA, contact your doctor right away.

Ask your health care provider any questions you may have about how to use Trelstar LA.

Important safety information:

• Trelstar LA may cause dizziness or vision changes. These effects may be worse if you take it with alcohol or certain medicines. Use Trelstar LA with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.


• Certain hormone levels may increase during the first few weeks of treatment with Trelstar LA. This may cause you to experience worsening symptoms or onset of new symptoms (eg, bone pain; blood in the urine; difficulty urinating; burning, numbness, or tingling) during the first few weeks of treatment. Patients with growths on or near the spine or spinal cord, or blockage of the bladder or ureters may be at greater risk of developing serious and sometimes fatal complications. Contact your doctor if any new or worsened symptoms occur while using Trelstar LA.


• Trelstar LA lowers the amount of certain hormones in your body. This may cause certain expected side effects to occur, such as breast enlargement, soreness, or tenderness; testicular changes, pain, or soreness; decreased sexual ability; hot flashes; or night sweats. Contact your doctor if you have questions or concerns or if you experience any of these side effects.


• A slight increase in the risk of stroke or serious and sometimes fatal heart problems has been reported with the use of GnRH agonists in men. Although the risk appears to be low, seek immediate medical attention if you experience chest, jaw, or left arm pain; confusion; fainting; numbness of an arm or leg; one-sided weakness; slurred speech; sudden, severe headache or vomiting; or vision changes. Discuss any questions or concerns with your doctor.


• Trelstar LA may raise your blood sugar. High blood sugar may make you feel confused, drowsy, or thirsty. It can also make you flush, breathe faster, or have a fruit-like breath odor. If these symptoms occur, tell your doctor right away.


• Diabetes patients - Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.


• Rarely, a serious pituitary gland problem (pituitary apoplexy) may occur after you use Trelstar LA. This serious problem usually occurs shortly after you begin to use Trelstar LA. Contact your doctor immediately if you experience a sudden headache, vomiting, fainting, eye weakness, inability to move your eyes, mental status changes, or vision changes.


• Trelstar LA may interfere with certain lab tests, including certain hormone and pituitary gland function tests. Be sure your doctor and lab personnel know you are using Trelstar LA.


• Lab tests, including testosterone,prostate specific antigen (PSA) levels, hemoglobin A_1c, or blood glucose, may be performed while you use Trelstar LA. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.


• Use Trelstar LA with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.


• PREGNANCY and BREAST-FEEDING: Trelstar LA may cause harm to the fetus. Do not become pregnant while you are using it. If you think you may be pregnant, contact your doctor right away. You will need to discuss the benefits and risks of using Trelstar LA while you are pregnant. It is not known if Trelstar LA is found in breast milk. Do not breast-feed while using Trelstar LA.

Possible side effects of Trelstar LA:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Change in breast size; constipation; decreased sexual desire or ability; diarrhea; dizziness; headache; hot flashes; itching, pain, redness, or swelling at the injection site; loss of appetite; nausea; sleeplessness; stomach discomfort; tiredness or weakness; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness); back pain; blood in the urine or dark urine; bone pain; breast pain; burning, numbness, or tingling; calf or leg pain or tenderness; fainting; fast or irregular heartbeat; fever, chills, or persistent sore throat; mood or mental changes (eg, depression); painful urination; severe or persistent headache, drowsiness, or dizziness; severe or persistent joint, muscle, or back pain; severe or persistent leg cramps; shortness of breath; sudden, unusual weight gain; swelling of the hands, ankles, feet or legs; symptoms of heart attack (eg, chest, jaw, or left arm pain; numbness of an arm or leg; sudden, severe headache or vomiting); symptoms of high blood sugar (eg, drowsiness; fast breathing; flushing; fruit-like breath odor; increased thirst, hunger, or urination); symptoms of stroke (eg, confusion, one-sided weakness, slurred speech); trouble urinating or inability to urinate; unusual tiredness or weakness; vision changes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Trelstar LA side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.

Proper storage of Trelstar LA:

Store Trelstar LA at room temperature between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Do not freeze. Discard any medicine not used immediately after mixing. Keep Trelstar LA, as well as needles and syringes, out of the reach of children and away from pets.

General information:

• If you have any questions about Trelstar LA, please talk with your doctor, pharmacist, or other health care provider.


• Trelstar LA is to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Trelstar LA. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Trelstar LA resources

• Trelstar LA Side Effects (in more detail)
• Trelstar LA Use in Pregnancy & Breastfeeding
• Trelstar LA Drug Interactions
• Trelstar LA Support Group
• 1 Review for Trelstar LA - Add your own review/rating

• Trelstar LA Prescribing Information (FDA)


• Trelstar LA Advanced Consumer (Micromedex) - Includes Dosage Information


• Trelstar LA Concise Consumer Information (Cerner Multum)


• Trelstar Depot Prescribing Information (FDA)


• Triptorelin Pamoate Monograph (AHFS DI)

Compare Trelstar LA with other medications

• Prostate Cancer

Metotreksat

Metotreksat may be available in the countries listed below.

Ingredient matches for Metotreksat

Methotrexate

Methotrexate sodium salt (a derivative of Methotrexate) is reported as an ingredient of Metotreksat in the following countries:

• Bosnia & Herzegowina


• Slovenia

International Drug Name Search

Aquacel

Aquacel may be available in the countries listed below.

Ingredient matches for Aquacel

Carmellose

Carmellose is reported as an ingredient of Aquacel in the following countries:

• Argentina


• South Africa

International Drug Name Search

Donecil

Donecil may be available in the countries listed below.

Ingredient matches for Donecil

Donepezil

Donepezil is reported as an ingredient of Donecil in the following countries:

• Peru

International Drug Name Search

Tretinoin Liquid

Pronunciation: TREH-tih-noyn
Generic Name: Tretinoin
Brand Name: Retin-A

Tretinoin Liquid is used for:

Treating acne. It may also be used for other conditions as determined by your doctor.

Tretinoin Liquid is a vitamin A derivative. How it exerts its beneficial effects against acne is not fully known. Tretinoin appears to increase skin-cell turnover and to reduce the tendency for skin cells to stick together. This reduces the formation of acne and allows quicker healing of acne that does develop.

Do NOT use Tretinoin Liquid if:

• you are allergic to any ingredient in Tretinoin Liquid

Contact your doctor or health care provider right away if any of these apply to you.

Before using Tretinoin Liquid:

Some medical conditions may interact with Tretinoin Liquid. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you have eczema, an abnormally high white blood cell count, or a sunburn

Some MEDICINES MAY INTERACT with Tretinoin Liquid. Because little, if any, of Tretinoin Liquid is absorbed into the blood, the risk of it interacting with another medicine is low.

Ask your health care provider if Tretinoin Liquid may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Tretinoin Liquid:

Use Tretinoin Liquid as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Tretinoin Liquid is for external use only.


• Apply a thin film of medicine to the affected area using a fingertip, gauze pad, or cotton swab. Be careful that Tretinoin Liquid does not run onto skin that is not being treated.


• Remove all cosmetics with a mild soap before applying Tretinoin Liquid. Gently dry the area. Wait 20 to 30 minutes to make sure that your skin is completely dry.


• Wash your hands immediately after using Tretinoin Liquid.


• If you miss a dose of Tretinoin Liquid, skip the missed dose and go back to your regular dosing schedule.

Ask your health care provider any questions you may have about how to use Tretinoin Liquid.

Important safety information:

• Avoid getting Tretinoin Liquid in your eyes, nose, or mouth, or on the outside of your nose. If you get Tretinoin Liquid in your eyes, rinse thoroughly with water.


• Tretinoin Liquid may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to Tretinoin Liquid. Use a sunscreen (minimum SPF 15) or wear protective clothing if you must be outside for more than a short time.


• For the first 2 to 3 weeks of treatment, your skin condition may appear to worsen. This is expected. Do not stop using Tretinoin Liquid at this time.


• Talk with your doctor before you use any other medicines or products on your skin. While you are using Tretinoin Liquid, you may use cosmetics.


• Do not apply Tretinoin Liquid to skin that is sunburned. Wait until the burn is fully healed before using Tretinoin Liquid.


• Do NOT use more than the recommended dose or use for longer than prescribed without checking with your doctor.


• Avoid using other topical medication, cosmetics, or other products that have a strong drying effect. If you have dry skin from using these products, allow your skin to "rest" before using Tretinoin Liquid.


• Do not use Tretinoin Liquid for any condition other than that for which it was prescribed.


• Weather extremes, such as windy or cold weather, may irritate your skin more while you are using Tretinoin Liquid.


• Tretinoin Liquid may cause harm if it is swallowed. If you may have taken it by mouth, contact your poison control center or emergency room right away.


• Tretinoin Liquid is flammable. Do not store or use near an open flame.


• PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Tretinoin Liquid while you are pregnant. It is not known if Tretinoin Liquid is found in breast milk. If you are or will be breast-feeding while you use Tretinoin Liquid, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Tretinoin Liquid:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Redness, peeling at application site; sensitivity to sunlight; skin irritation; warmth or stinging at application site.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); change in skin color; severe redness, peeling, swelling, blistering, or crusting of the skin.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include clumsiness; dizziness; excessive redness, peeling, and discomfort; flushing; headache; stomach pain.

Proper storage of Tretinoin Liquid:

Store Tretinoin Liquid at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store in a tightly closed container. Store away from heat and light. Do not store in the bathroom. Keep Tretinoin Liquid out of the reach of children and away from pets.

General information:

• If you have any questions about Tretinoin Liquid, please talk with your doctor, pharmacist, or other health care provider.


• Tretinoin Liquid is to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Tretinoin Liquid. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Tretinoin resources

• Tretinoin Use in Pregnancy & Breastfeeding
• Tretinoin Drug Interactions
• Tretinoin Support Group
• 42 Reviews for Tretinoin - Add your own review/rating

Compare Tretinoin with other medications

• Acne
• Lichen Sclerosus
• Necrobiosis Lipoidica Diabeticorum
• Photoaging of the Skin

Apo-Haloperidol

Generic Name: haloperidol (Oral route)

hal-oh-PER-i-dol

Oral route(Tablet)

Elderly patients with dementia-related psychosis treated with atypical antipsychotic drugs are at an increased risk of death compared to placebo. Although the causes of death in clinical trials were varied, most of the deaths appeared to be either cardiovascular (eg, heart failure, sudden death) or infectious (eg, pneumonia) in nature. Observational studies suggest that antipsychotic drugs may increase mortality. It is unclear from these studies to what extent the mortality findings may be attributed to the antipsychotic drug as opposed to patient characteristics. Haloperidol is not approved for the treatment of patients with dementia-related psychosis .

Commonly used brand name(s)

In the U.S.

• Haldol

In Canada

• Alti-Haloperidol


• Apo-Haloperidol


• Novo-Peridol


• Peridol


• Pms-Haloperidol


• Ratio-Haloperidol

Available Dosage Forms:

• Tablet


• Solution

Therapeutic Class: Antipsychotic

Pharmacologic Class: Dopamine Antagonist

Chemical Class: Butyrophenone

Uses For Apo-Haloperidol

Haloperidol is used to treat nervous, emotional, and mental conditions (e.g., schizophrenia). It is also used to control the symptoms of Tourette's disorder. This medicine should not be used to treat behavior problems in older adult patients who have dementia.

Haloperidol is also used to treat severe behavioral problems (e.g., aggressive, impulsive behavior) or hyperactivity in children who have already been treated with psychotherapy or other medicines that did not work well.

This medicine is available only with your doctor's prescription.

Before Using Apo-Haloperidol

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of haloperidol in children younger than 3 years of age. Safety and efficacy have not been established.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of haloperidol in the elderly. However, elderly women are more likely to have a side effect called tardive dyskinesia, and elderly patients are more likely to have age-related heart problems, which may require an adjustment in the dose for patients receiving haloperidol.

Pregnancy

	Pregnancy Category	Explanation
All Trimesters	C	Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

• Bepridil


• Cisapride


• Dronedarone


• Levomethadyl


• Mesoridazine


• Metoclopramide


• Pimozide


• Sparfloxacin


• Terfenadine


• Thioridazine

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Acecainide


• Ajmaline


• Alfuzosin


• Amiodarone


• Amisulpride


• Amitriptyline


• Amoxapine


• Apomorphine


• Aprindine


• Arsenic Trioxide


• Asenapine


• Astemizole


• Azimilide


• Azithromycin


• Bretylium


• Chloral Hydrate


• Chloroquine


• Chlorpromazine


• Ciprofloxacin


• Citalopram


• Clarithromycin


• Clomipramine


• Clozapine


• Crizotinib


• Dalfopristin


• Dasatinib


• Desipramine


• Dibenzepin


• Disopyramide


• Dofetilide


• Dolasetron


• Doxepin


• Droperidol


• Encainide


• Enflurane


• Erythromycin


• Flecainide


• Fluconazole


• Fluoxetine


• Foscarnet


• Gatifloxacin


• Gemifloxacin


• Granisetron


• Halofantrine


• Halothane


• Hydromorphone


• Hydroquinidine


• Ibutilide


• Imipramine


• Isoflurane


• Isradipine


• Ketoconazole


• Lapatinib


• Levofloxacin


• Lidoflazine


• Lithium


• Lopinavir


• Lorcainide


• Lumefantrine


• Mefloquine


• Methadone


• Milnacipran


• Moxifloxacin


• Nilotinib


• Norfloxacin


• Nortriptyline


• Octreotide


• Ofloxacin


• Ondansetron


• Paliperidone


• Paroxetine


• Pazopanib


• Pentamidine


• Perflutren Lipid Microsphere


• Pirmenol


• Posaconazole


• Prajmaline


• Probucol


• Procainamide


• Prochlorperazine


• Promethazine


• Propafenone


• Propranolol


• Protriptyline


• Quetiapine


• Quinidine


• Quinine


• Quinupristin


• Ranolazine


• Risperidone


• Salmeterol


• Saquinavir


• Sematilide


• Sertindole


• Sodium Phosphate


• Sodium Phosphate, Dibasic


• Sodium Phosphate, Monobasic


• Solifenacin


• Sorafenib


• Sotalol


• Spiramycin


• Sulfamethoxazole


• Sultopride


• Sunitinib


• Tedisamil


• Telavancin


• Telithromycin


• Tetrabenazine


• Toremifene


• Tramadol


• Trazodone


• Trifluoperazine


• Trimethoprim


• Trimipramine


• Vandetanib


• Vardenafil


• Vasopressin


• Vemurafenib


• Venlafaxine


• Voriconazole


• Ziprasidone


• Zolmitriptan


• Zotepine

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Benztropine


• Betel Nut


• Bupropion


• Buspirone


• Carbamazepine


• Dextromethorphan


• Fluvoxamine


• Methyldopa


• Nefazodone


• Olanzapine


• Procyclidine


• Rifampin


• Rifapentine


• Tacrine


• Trihexyphenidyl

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

• Breast cancer, history of or


• Chest pain or


• Heart or blood vessel disease, severe or


• Hyperprolactinemia (high prolactin in the blood) or


• Hypotension (low blood pressure) or


• Mania or


• Neuroleptic malignant syndrome, history of or


• Seizures or epilepsy, history of—Use with caution. May make these conditions worse.

• Central nervous system depression, severe or


• Coma or


• Dementia in elderly or


• Parkinson's disease—Should not be used in patients with these conditions.

• Heart rhythm problems (e.g., familial long QT-syndrome), history of or


• Hypokalemia (low potassium in the blood) or


• Hypomagnesemia (low magnesium in the blood) or


• Hypothyroidism (underactive thyroid) or


• Thyrotoxicosis (overactive thyroid)—May increase risk for more serious side effects.

Proper Use of haloperidol

This section provides information on the proper use of a number of products that contain haloperidol. It may not be specific to Apo-Haloperidol. Please read with care.

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. This is particularly important for elderly patients, since they may react very strongly to this medicine.

For patients taking the liquid form of this medicine:

• This medicine is to be taken by mouth and it comes in a dropper bottle. Each dose is to be measured with the specially marked dropper provided with your bottle. Do not use other droppers since they may not deliver the correct amount of medicine.


• This medicine should be mixed with water or a beverage, such as orange juice, apple juice, tomato juice, or cola, and taken immediately after mixing.

Continue taking this medicine for the full time of treatment. Sometimes haloperidol must be taken for several days to several weeks before its full effect is reached.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

• For oral dosage forms (solution and tablets):
  
  • For nervous, emotional, or mental conditions:
    
    • Adults and teenagers—At first, 0.5 to 5 milligrams (mg) two or three times a day. Your doctor may increase your dose if needed. However, the dose is usually not more than 100 mg per day.
    
    
    • Older adults—At first, 0.5 to 2 milligrams (mg) two or three times a day. Your doctor may increase your dose if needed. However, the dose is usually not more than 100 mg per day.
    
    
    • Children 3 to 12 years of age or weighing 15 to 40 kilograms (kg)—Dose is based on body weight and must be determined by your doctor. The usual dose is 50 to 150 micrograms per kg per day, given in divided doses two or three times a day. Your doctor may increase your dose if needed. However, the dose is usually not more than 6 mg per day.
    
    
    • Children below 3 years of age—Use and dose must be determined by the doctor.
    
    
  
  

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Precautions While Using Apo-Haloperidol

Your doctor should check your progress at regular visits, especially during the first few months of treatment with this medicine. The amount of haloperidol you take may be changed to meet the needs of your condition and to prevent side effects.

Do not stop taking this medicine without checking first with your doctor. Your doctor may want you to gradually reduce the amount you are taking before stopping completely. This will allow your body time to adjust and help avoid a worsening of your medical condition.

This medicine will add to the effects of alcohol and other CNS depressants (medicines that make you drowsy or less alert). Some examples of CNS depressants are antihistamines or medicine for allergies or colds; sedatives, tranquilizers, or sleeping medicine; prescription pain medicine or narcotics; medicine for seizures or barbiturates; muscle relaxants; or anesthetics, including some dental anesthetics. Check with your doctor before taking any of the above while you are using this medicine.

This medicine may cause some people to become dizzy, drowsy, or less alert than they are normally, especially as the amount of medicine is increased. Even if you take haloperidol at bedtime, you may feel drowsy or less alert on arising. Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangerous if you are dizzy or not alert.

Dizziness, lightheadedness, or fainting may occur, especially when you get up from a lying or sitting position. Getting up slowly may help. If this problem continues or gets worse, check with your doctor.

This medicine will often make you sweat less, causing your body temperature to increase. Use extra care not to become overheated during exercise or hot weather while you are taking this medicine, since overheating may result in heat stroke. Also, hot baths or saunas may make you feel dizzy or faint while you are using this medicine.

Haloperidol may cause your skin to be more sensitive to sunlight than it is normally. Exposure to sunlight, even for brief periods of time, may cause a skin rash, itching, redness or other discoloration of the skin, or a severe sunburn. When you begin taking this medicine:

• Stay out of direct sunlight, especially between the hours of 10:00 a.m. and 3:00 p.m., if possible.


• Wear protective clothing, including a hat or sunglasses.


• Apply a sun block product that has a skin protection factor (SPF) of at least 15. Some patients may require a product with a higher SPF number, especially if they have a fair complexion. If you have any questions about this, check with your doctor.


• Apply a sun block lipstick that has an SPF of at least 15 to protect your lips.


• Do not use a sunlamp or tanning bed or booth.

If you have a severe reaction from the sun, check with your doctor.

Haloperidol may cause dry mouth. For temporary relief, use sugarless candy or gum, melt bits of ice in your mouth, or use a saliva substitute. However, if your mouth continues to feel dry for more than 2 weeks, check with your medical doctor or dentist. Continuing dryness of the mouth may increase the chance of dental disease, including tooth decay, gum disease, and fungus infections.

Contact your doctor as soon as possible if you have chest pain or discomfort, a fast heartbeat, trouble breathing, or fever and chills. These can be symptoms of a very serious problem with your heart.

This medicine may cause tardive dyskinesia (a movement disorder). Check with your doctor right away if you have any of the following symptoms while taking this medicine: lip smacking or puckering, puffing of the cheeks, rapid or worm-like movements of the tongue, uncontrolled chewing movements, or uncontrolled movements of the arms and legs.

Stop taking this medicine and check with your doctor right away if you have any of the following symptoms while using this medicine: convulsions (seizures); difficulty with breathing; a fast heartbeat; a high fever; high or low blood pressure; increased sweating; loss of bladder control; severe muscle stiffness; unusually pale skin; or tiredness. These could be symptoms of a serious condition called neuroleptic malignant syndrome (NMS).

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

Apo-Haloperidol Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

• Difficulty with speaking or swallowing


• inability to move the eyes


• loss of balance control


• mask-like face


• muscle spasms, especially of the neck and back


• restlessness or need to keep moving (severe)


• shuffling walk


• stiffness of the arms and legs


• trembling and shaking of the fingers and hands


• twisting movements of the body


• weakness of the arms and legs

Less common

• Decreased thirst


• difficulty in urination


• dizziness, lightheadedness, or fainting


• hallucinations (seeing or hearing things that are not there)


• lip smacking or puckering


• puffing of the cheeks


• rapid or worm-like movements of the tongue


• skin rash


• uncontrolled chewing movements


• uncontrolled movements of the arms and legs

Rare

• Confusion


• convulsions (seizures)


• difficult or fast breathing


• fast heartbeat or irregular pulse


• fever (high)


• high or low blood pressure


• hot, dry skin, or lack of sweating


• increased blinking or spasms of the eyelid


• increased sweating


• loss of bladder control


• muscle stiffness (severe)


• muscle weakness


• sore throat and fever


• uncontrolled twisting movements of the neck, trunk, arms, or legs


• unusual bleeding or bruising


• unusual facial expressions or body positions


• unusual tiredness or weakness


• unusually pale skin


• yellow eyes or skin

Incidence not known

• Continuing nausea or vomiting


• increase in the frequency of seizures


• loss of appetite


• swelling of the face


• tiredness and weakness

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose

• Difficulty with breathing (severe)


• dizziness (severe)


• drowsiness (severe)


• muscle trembling, jerking, stiffness, or uncontrolled movements (severe)


• unusual tiredness or weakness (severe)

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

• Blurred vision


• changes in menstrual period


• constipation


• dryness of the mouth


• swelling or pain in the breasts (in females)


• unusual secretion of milk


• weight gain

Less common

• Decreased sexual ability


• drowsiness


• increased sensitivity of the skin to sun (skin rash, itching, redness or other discoloration of skin, or severe sunburn)


• nausea or vomiting

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: Apo-Haloperidol side effects (in more detail)

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.

More Apo-Haloperidol resources

• Apo-Haloperidol Side Effects (in more detail)
• Apo-Haloperidol Use in Pregnancy & Breastfeeding
• Drug Images
• Apo-Haloperidol Drug Interactions
• Apo-Haloperidol Support Group
• 13 Reviews for Apo-Haloperidol - Add your own review/rating

Compare Apo-Haloperidol with other medications

• Dementia
• ICU Agitation
• Mania
• Nausea/Vomiting
• Psychosis
• Tourette's Syndrome

Roferon HSA

Roferon HSA may be available in the countries listed below.

Ingredient matches for Roferon HSA

Interferon alfa

Interferon alfa Interferon alfa-2b (Arg-23; His-34) (a derivative of Interferon alfa) is reported as an ingredient of Roferon HSA in the following countries:

• Peru

International Drug Name Search